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Vitamin D and Regulation of Pericyte Function
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Jamali, Nasim. |
| 단체저자명 | The University of Wisconsin - Madison. Cellular anf Molecular Biology. |
| 서명/저자사항 | Vitamin D and Regulation of Pericyte Function. |
| 발행사항 | [S.l.] : The University of Wisconsin - Madison., 2017 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2017 |
| 형태사항 | 372 p. |
| 소장본 주기 | School code: 0262. |
| ISBN | 9780438029828 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Nader Sheibani. |
| 요약 | Vitamin D deficiency has been linked to pathogenesis of many diseases including cardiovascular, cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation of immune function, inflammation, angiogenesis, and ag |
| 요약 | The majority of vitamin D action is mediated through vitamin D receptor (Vdr). However, the role Vdr expression plays in vascular development and inhibition of neovascularization by vitamin D remained unknown. In chapter two, I determined the im |
| 요약 | Our previous studies indicated that calcitriol has no significant effect on retinal EC function in culture. However, calcitriol inhibited capillary morphogenesis of EC in Matrigel. As PC, play essential roles during angiogenesis, including vascu |
| 요약 | To further investigate whether the observed effects of calcitriol on PC is organ specific, I also evaluated the response of lung PC to calcitriol. Similar to retinal PC, calcitriol reduced proliferation and migration of lung PC as well as increa |
| 요약 | Taken together, these studies established an important role for vitamin D and its receptor in regulation of perivascular supporting cell function. I propose Vdr expression is important during maturation of developing vasculature by promoting the |
| 일반주제명 | Cellular biology. Molecular biology. Biology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14996651 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028985 | 574 | 가야대학교// | 대출가능 |
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