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Renal Tubular Transport of Drugs in Healthy and Diseased Kidney
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Chapron, Alenka. |
| 단체저자명 | University of Washington. Pharmaceutics. |
| 서명/저자사항 | Renal Tubular Transport of Drugs in Healthy and Diseased Kidney. |
| 발행사항 | [S.l.] : University of Washington., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 176 p. |
| 소장본 주기 | School code: 0250. |
| ISBN | 9780438177734 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Danny D. Shen. |
| 요약 | In this thesis work, I applied traditional and innovative bioengineering approaches to develop an in vitro model of renal proximal tubule with human proximal tubule epithelial cells (PTECs) that is particularly suited for drug transport studies. |
| 요약 | At the initial stage of our development, freshly isolated human PTECs were successfully expanded through conventional culturing, which afforded an adequate cell source. When passaged PTECs were grown on permeable supports, they maintained their |
| 요약 | The last part of my thesis work focused on alterations in renal secretory clearance of drugs in renal impairment. Dosing adjustments in chronic kidney diseases (CKD) have traditionally relied on serum creatinine as a biomarker of glomerular filt |
| 일반주제명 | Pharmaceutical sciences. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999199 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028508 | 615 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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