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The Role of CS1 Fibronectin in HIV-1 Infection of alpha 4beta7+ T Lymphocytes
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Plotnik, David Alan. |
| 단체저자명 | University of Washington. Pharmaceutics. |
| 서명/저자사항 | The Role of CS1 Fibronectin in HIV-1 Infection of alpha 4beta7+ T Lymphocytes. |
| 발행사항 | [S.l.] : University of Washington., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 198 p. |
| 소장본 주기 | School code: 0250. |
| ISBN | 9780438177345 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Shiu-Lok Hu. |
| 요약 | A hallmark of Human Immunodeficiency Virus type 1 (HIV-1) pathogenesis is the profound depletion of CD4+ T lymphocytes within gut-associated lymphoid tissues (GALT), and persistent immune dysfunction at mucosal sites. It has been demonstrated th |
| 요약 | In this dissertation, I investigated the basis for HIV-alpha4 beta7 interaction in detail. I discovered that gp120 does not bind to alpha4beta7 as previously reported. Instead, I discovered that mammalian cell lines used to express recombinant g |
| 요약 | Collectively, these studies clarified the nature of HIV interactions with alpha4beta7, identified a novel role for fibronectins in HIV pathogenesis, and provided insight into how these interactions may be targeted therapeutically. |
| 일반주제명 | Virology. Pharmaceutical sciences. Molecular biology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999178 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028492 | 576.6 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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