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Boston University Henry M. Goldman School of Dental Medicine

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개인저자Alwafi, Hanadi A.
단체저자명Boston University. Pediatric Dentistry GSDM.
서명/저자사항Boston University Henry M. Goldman School of Dental Medicine.
발행사항[S.l.] : Boston University., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항230 p.
소장본 주기School code: 0017.
ISBN9780438041981
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Laisheng Chou.
요약Background: Thymoquinone (TQ) is one of the most active ingredients of Nigella sativa seed. TQ has a variety of pharmacologic properties including possess antinociceptive, antibacterial, anti-inflammatory, anti-oxidative activities and osteogeni
요약Purpose: This study evaluates the effect of TQ on the attachment efficiency, proliferation, and odontogenic differentiation of Human Dental Pulp Cells (HDPC's). The effect of TQ on odontogenic differentiation was also determined by evaluating al
요약Methods: Human dental pulp cells were cultured in triplicate using growth media with various TQ concentrations: 5 muM, 10muM, 15muM, 30muM, and 10muM as a control group at 7 and 21 days. Crystal violet staining was used to determine cell attachm
요약Results: Higher cell attachment efficiency was shown in all TQ groups at 16 hours (P<. 0001) except for the 5 muM group. A significantly higher cell proliferation rate was shown with low TQ concentration 5 muM at 7 days (P<. 0001) and at 21days
요약Conclusion: All tested TQ concentrations significantly enhanced cell attachment efficiency at 16 hours except TQ =5 muM. Cell proliferation rates were increased significantly by low TQ concentration 5 muM, and decreased significantly with higher
일반주제명Dentistry.
Biology.
언어영어
기본자료 저록Dissertation Abstracts International79-10B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14999172

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