| LDR | | 02539nmm uu200445 4500 |
| 001 | | 000000334154 |
| 005 | | 20240805175234 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438041981 |
| 035 | |
▼a (MiAaPQ)AAI10828486 |
| 035 | |
▼a (MiAaPQ)bu:13980 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 617.6 |
| 100 | 1 |
▼a Alwafi, Hanadi A. |
| 245 | 10 |
▼a Boston University Henry M. Goldman School of Dental Medicine. |
| 260 | |
▼a [S.l.] :
▼b Boston University.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 230 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Adviser: Laisheng Chou. |
| 502 | 1 |
▼a Thesis (D.Sc.D.)--Boston University, 2018. |
| 520 | |
▼a Background: Thymoquinone (TQ) is one of the most active ingredients of Nigella sativa seed. TQ has a variety of pharmacologic properties including possess antinociceptive, antibacterial, anti-inflammatory, anti-oxidative activities and osteogeni |
| 520 | |
▼a Purpose: This study evaluates the effect of TQ on the attachment efficiency, proliferation, and odontogenic differentiation of Human Dental Pulp Cells (HDPC's). The effect of TQ on odontogenic differentiation was also determined by evaluating al |
| 520 | |
▼a Methods: Human dental pulp cells were cultured in triplicate using growth media with various TQ concentrations: 5 muM, 10muM, 15muM, 30muM, and 10muM as a control group at 7 and 21 days. Crystal violet staining was used to determine cell attachm |
| 520 | |
▼a Results: Higher cell attachment efficiency was shown in all TQ groups at 16 hours (P<. 0001) except for the 5 muM group. A significantly higher cell proliferation rate was shown with low TQ concentration 5 muM at 7 days (P<. 0001) and at 21days |
| 520 | |
▼a Conclusion: All tested TQ concentrations significantly enhanced cell attachment efficiency at 16 hours except TQ =5 muM. Cell proliferation rates were increased significantly by low TQ concentration 5 muM, and decreased significantly with higher |
| 590 | |
▼a School code: 0017. |
| 650 | 4 |
▼a Dentistry. |
| 650 | 4 |
▼a Biology. |
| 690 | |
▼a 0567 |
| 690 | |
▼a 0306 |
| 710 | 20 |
▼a Boston University.
▼b Pediatric Dentistry GSDM. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0017 |
| 791 | |
▼a D.Sc.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14999172
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |