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Cardiomyocyte Cell Cycle Revealed by FUCCI
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Alvarez, Roberto, Jr. |
| 단체저자명 | University of California, San Diego. Biology. |
| 서명/저자사항 | Cardiomyocyte Cell Cycle Revealed by FUCCI. |
| 발행사항 | [S.l.] : University of California, San Diego., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 120 p. |
| 소장본 주기 | School code: 0033. |
| ISBN | 9780438110045 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Mark A. Sussman. |
| 요약 | Rationale: Pre-existing cardiomyocytes and resident cardiac stem cells are limited in their capacity for substantial regeneration in postnatal endogenous mammalian myocardial repair. Evidence for adult cardiomyocyte proliferation remains inconcl |
| 요약 | Objective: Authenticate fidelity of proliferative markers as indicators of de novo cardiomyogenesis and subsequently delineate the post-mitotic status of postnatal cardiomyocytes. |
| 요약 | Methods and Results: Cardiomyocyte specific FUCCI expression driven by the alpha-myosin heavy chain (alphaMHC) promoter was utilized in conjunction with traditional proliferation markers to identify cell cycle status of postnatal murine cardiomy |
| 요약 | Conclusions: Proliferation markers used to identify de novo cardiomyogenesis failed to distinguish cycling cardiomyocytes after injury. Adult cardiomyocytes upregulated cell cycle activity in response to sham injury but failed to complete regene |
| 일반주제명 | Biology. Cellular biology. Molecular biology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999048 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028357 | 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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