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Relationships Between Bacteria, Exacerbations, and Hospitalizations in Chronic Obstructive Pulmonary Disease

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개인저자Jacobs, David Matthew.
단체저자명State University of New York at Buffalo. Epidemiology and Environmental Health.
서명/저자사항Relationships Between Bacteria, Exacerbations, and Hospitalizations in Chronic Obstructive Pulmonary Disease.
발행사항[S.l.] : State University of New York at Buffalo., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항132 p.
소장본 주기School code: 0656.
ISBN9780438048140
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Heather M. Ochs-Balcom.
요약Bacteria within the lower respiratory tract plays a critical role in the clinical course and pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that acute exacerbations are attributable to bacteria, and these exacerb
요약The first part of this dissertation investigates the clinical impact of P. aeruginosa isolation in an outpatient COPD cohort. P. aeruginosa is an important pathogen in choric airway diseases including cystic fibrosis and bronchiectasis, signifi
요약Therefore, this aim investigated the association of P. aeruginosa isolation with long-term mortality and patient outcomes (exacerbations and hospitalizations) in a sample of U.S. veterans with COPD (n=181). After adjustment for age and pulmonar
요약The second part of the dissertation investigated bacterial colonization patterns and interactions among the four primary bacterial pathogens. Interspecies bacterial interactions can alter the composition of a microbial community and potentially
요약This aim evaluated the prevalence of bacterial colonization and determined species-specific interactions using sputum cultures collected at monthly visits in a sample of veterans with COPD over a 20 year period (n=8,843 clinic visits). Our findi
요약For our third aim, we shifted to a health-services focus in order to further understand the causes and factors related to 30-day readmission for an acute exacerbation of COPD. This was prompted based on the recent inclusion of COPD discharges as
일반주제명Epidemiology.
언어영어
기본자료 저록Dissertation Abstracts International79-10B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14998306

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