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Engineering protein-based biomaterials using SpyTag/SpyCatcher technology
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Williams, Danielle Marie. |
| 단체저자명 | Yale University. |
| 서명/저자사항 | Engineering protein-based biomaterials using SpyTag/SpyCatcher technology. |
| 발행사항 | [S.l.] : Yale University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 125 p. |
| 소장본 주기 | School code: 0265. |
| ISBN | 9780438269507 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Lynne Regan. |
| 요약 | The ability to create linkages using SpyTag/SpyCatcher technology is a powerful tool for protein design and engineering. SpyTag, a 13-residue peptide, and SpyCatcher, a small protein, interact spontaneously to form a covalent isopeptide bond, wh |
| 요약 | One such project involves the design of stimulus-responsive hydrogels made entirely of protein components. We took advantage of the modular nature of TPR domains, which bind C-terminal peptides, to interact with cognate peptide cross-linkers to |
| 요약 | Other projects described in this text involve the development of geometric protein arrays. Such arrays have implications in signal amplification, biosensing, and enzyme scaffolding array. Using the modular, rod-like protein SasG and SpyTag/SpyCa |
| 요약 | Finally, we were able to functionalize 2D surfaces and microcapsules using SpyTag/SpyCatcher technology and a unique, amphiphilic bacterial hydrophobin, Bs1A. Bs1A self-assembles into a stable monolayer at both air-water and water-oil interfaces |
| 일반주제명 | Biochemistry. Biophysics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15001240 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00026501 | 574 | 가야대학교// | 대출가능 |
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