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Understanding the Thermodynamics and Oral Absorption Potential of Pharmaceutical Amorphous Solid Dispersions
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Setiawan, Nico. |
| 단체저자명 | University of Kentucky. Pharmacy. |
| 서명/저자사항 | Understanding the Thermodynamics and Oral Absorption Potential of Pharmaceutical Amorphous Solid Dispersions. |
| 발행사항 | [S.l.] : University of Kentucky., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 159 p. |
| 소장본 주기 | School code: 0102. |
| ISBN | 9780438239340 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Patrick J. Marsac. |
| 요약 | Supersaturating drug delivery systems, such as amorphous solid dispersions (ASDs), have been used extensively to elevate the apparent solubility and oral bioavailability of poorly water-soluble drugs. However, despite the numerous examples of su |
| 요약 | Further, ASDs must dissolve after administration and maintain the intended supersaturation in the gastrointestinal (GI) tract during the GI transit time to achieve maximum oral absorption. In solution, the energetics advantage of the amorphous o |
| 요약 | 1. The relative thermodynamics magnitude of various processes with respect to the crystallization energy associated with amorphous drugs 2. The development of a practical tool to measure the thermodynamic activity of amorphous materials over its |
| 일반주제명 | Pharmaceutical sciences. Chemical engineering. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15001224 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00026486 | 615 | 가야대학교// | 대출가능 |
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