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Statistical Methods for Chip-Exo/Nexus Quality Control, and Fine-mapping of Multi-trait SNPs in High LD by Using Next-generation Sequencing Data
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Welch, Rene. |
| 단체저자명 | The University of Wisconsin - Madison. Statistics. |
| 서명/저자사항 | Statistical Methods for Chip-Exo/Nexus Quality Control, and Fine-mapping of Multi-trait SNPs in High LD by Using Next-generation Sequencing Data. |
| 발행사항 | [S.l.] : The University of Wisconsin - Madison., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 110 p. |
| 소장본 주기 | School code: 0262. |
| ISBN | 9780438359758 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Sunduz Keles. |
| 요약 | Advances in the field of genomics over the last years have led to diverse types of measurements with vast amounts of next generation sequencing (NGS) data. As genomic measurements become faster and cheaper with higher-throughput technologies, la |
| 요약 | In this thesis we introduce two methods. First, we present ChIPexoQual, an R/Bioconductor quality control pipeline that enables exploration and analysis of ChIP-exo and related experiments. ChIPexoQual evaluates a number of key issues including |
| 요약 | Next, we introduce FM-HighLD, a fine-mapping method for variants in high linkage disequilibrium that, by using ChIP-seq based annotation data, is capable of calculating SNP probabilities for being causal for single or multiple traits by using an |
| 요약 | Finally, in this thesis, we showcase two R/Bioconductor packages to facilitate the analysis of next generation sequencing data, and explore RNA-seq differential expression results. First, ChIPUtils is a package that calculates typical ChIP-seq q |
| 일반주제명 | Statistics. Bioinformatics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15001170 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00026067 | 310 | 가야대학교// | 대출가능 |
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