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Differential Effects of Repeated Low-dose Ketamine on Cross-frequency Interactions in Naive and Preclinical Models of Movement Disorders
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Ye, Tony. |
| 단체저자명 | The University of Arizona. Psychology. |
| 서명/저자사항 | Differential Effects of Repeated Low-dose Ketamine on Cross-frequency Interactions in Naive and Preclinical Models of Movement Disorders. |
| 발행사항 | [S.l.] : The University of Arizona., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 190 p. |
| 소장본 주기 | School code: 0009. |
| ISBN | 9780438346093 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Stephen L. Cowen. |
| 요약 | Ketamine is a well-established anesthetic in high-doses that has been in use for over 50 years (Domino et al., 1965). At low sub-anesthetic doses, ketamine is therapeutically effective at treating a wide range of disorders such as treatment-resi |
| 요약 | Furthermore, ketamine may also have a therapeutic role in treating Parkinson's disease (PD). Hypersynchronous beta (15 -- 30 Hz) is the pathological oscillatory signature of PD. Additionally, gamma oscillations are pro-kinetic and voluntary move |
| 요약 | Using the experimental protocols of Bartlett and colleagues (2016) with the addition of measuring local-field potential activity, we show that the pathological oscillations associated with Parkinson's disease (e.g., beta (15 -- 30 Hz)) in 6-hydr |
| 요약 | Ketamine does produce differential effects on cross-frequency interactions. Ketamine enhanced coordination between low and high frequencies in the striatum, but with the opposite effect in the hippocampus. In LID animals, ketamine reverses theta |
| 일반주제명 | Neurosciences. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15001116 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00026021 | 616 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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