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Regulation of Effector CD4 T Cell Pathogenicity during Chronic Inflammation
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Shin, Boyoung. |
| 단체저자명 | The University of Alabama at Birmingham. Joint Health Sciences. |
| 서명/저자사항 | Regulation of Effector CD4 T Cell Pathogenicity during Chronic Inflammation. |
| 발행사항 | [S.l.] : The University of Alabama at Birmingham., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 148 p. |
| 소장본 주기 | School code: 0005. |
| ISBN | 9780438342866 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Laurie E. Harrington. |
| 요약 | Effector CD4 T cells are essential for the balance between pro- and anti-inflammatory immune responses during homeostasis. Dysregulation of effector CD4 T cell responses results in chronic inflammatory disorders such as Inflammatory Bowel Diseas |
| 요약 | Different subsets of effector CD4 T cells utilize distinct metabolic pathways. We find that Th17 differentiation occurs in conjunction with a robust increase of ATP-linked mitochondrial respiration, which fuels energy demand. Interestingly, mito |
| 요약 | We also find that the differentiation state of CD4 T cells contributes to pathogenicity. A transcriptome analysis of effector CD4 T cells from chronic intestinal inflammation reveals that CD4 T cells exist as a spectrum of differentiation states |
| 일반주제명 | Immunology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999798 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00025645 | 616.079 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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