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Methods for Adapting Global Mass Spectrometry Based Metabolomics to the Clinical Environment
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Wulff, Jacob Edward. |
| 단체저자명 | The University of North Carolina at Chapel Hill. Biostatistics. |
| 서명/저자사항 | Methods for Adapting Global Mass Spectrometry Based Metabolomics to the Clinical Environment. |
| 발행사항 | [S.l.] : The University of North Carolina at Chapel Hill., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 295 p. |
| 소장본 주기 | School code: 0153. |
| ISBN | 9780438348721 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Includes supplementary digital materials. Adviser: Lloyd J. Edwards. |
| 요약 | Metabolomics is a maturing field with successful application to research areas such as biomarker discovery and mechanisms of disease. With the ability to profile hundreds or even thousands of biochemicals simultaneously, many of which are also u |
| 요약 | The first paper explores basic properties of metabolites, specifically the statistical distribution of metabolite concentrations and correlation between them. In human sample sets covering three different sample material appropriate for clinical |
| 요약 | In the second paper, application of the log transformation is used to account for missing values in estimating population parameters of a reference cohort. Missing values are largely attributed to the true level falling below the detection limit |
| 요약 | The third paper addresses merging multiple global LC-MS metabolomic sets of the same biological sample type together. Typical normalization methods meant to account for sample to sample variation are presented and compared to alternative approac |
| 일반주제명 | Biostatistics. Analytical chemistry. Biochemistry. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999656 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00025498 | 574 | 가야대학교// | 대출가능 |
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