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Epigenetic Abnormalities in Brain Tumors
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Chen, Xiaoyue. |
| 단체저자명 | College of Medicine - Mayo Clinic. Biochemistry and Molecular Biology. |
| 서명/저자사항 | Epigenetic Abnormalities in Brain Tumors. |
| 발행사항 | [S.l.] : College of Medicine - Mayo Clinic., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 125 p. |
| 소장본 주기 | School code: 1542. |
| ISBN | 9780438117693 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Advisers: Zhiguo Zhang |
| 요약 | Epigenetics is the study of heritable changes that alters gene expression without changing DNA sequence. Previous studies showed that epigenetic alterations were associated with tumor initiation, progression and the development of chemo-resistan |
| 요약 | MGMT promoter methylation is one of the most important glioblastoma biomarkers. Hypermethylation of this promoter is associated with a lower MGMT expression and a higher efficacy of TMZ therapy. However, MGMT promoter methylation state does not |
| 요약 | Besides the development of resistance, epigenetic alterations play an important role in the initiation of DIPG. However, whether epigenetic alterations can be targeted to treat DIPG is unknown. In Chapter III, I show that inhibiting histone deme |
| 일반주제명 | Biology. Oncology. Molecular biology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999494 |
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인쇄
| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00025341 | DP 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출불가(별치) |
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