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Encapsulation of Nanoparticles and Polymers within Block Copolymer Micelles Prepared by the Emulsion and Solvent Evaporation Method

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자료유형	E-Book
개인저자	Nabar, Gauri Mangesh.
단체저자명	The Ohio State University. Chemical Engineering.
서명/저자사항	Encapsulation of Nanoparticles and Polymers within Block Copolymer Micelles Prepared by the Emulsion and Solvent Evaporation Method.
발행사항	[S.l.] : The Ohio State University., 2017
발행사항	Ann Arbor : ProQuest Dissertations & Theses, 2017
형태사항	316 p.
소장본 주기	School code: 0168.
ISBN	9780438098794
일반주기	Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. Advisers: Jessica Winter
요약	Nearly 90% of drugs in the developmental stage and most high quality nanoparticles used in the detection and treatment of various medical conditions are poorly soluble in the aqueous physiological environment. This has led to a very high demand
요약	This dissertation covers the following broad areas: (1) encapsulation of polymers and nanoparticles into micelles (2) effect of process additives and external fields on micelle functionality (3) effect of processing conditions on micelle morphol
요약	Encapsulation studies: We found that the emulsion and solvent evaporation method could yield high encapsulation of polymers in micelles. We developed a unique hybrid micelle formulation for drug delivery by encapsulating high molecular weight po
요약	Additives and external fields: Surfactants used during micelle preparation had a surprising effect on the fluorescence of quantum dot loaded micelles. Surfactants that increased the density of the micelle coating around the encapsulated quantum
요약	External magnetic fields could impact the ordering of magnetic nanoparticles within micelles. This effect was even stronger when the external magnetic field was applied during the encapsulation of magnetic nanoparticles into micelles.
요약	Processing conditions: Altering the solvent evaporation rate dramatically influenced micelle morphology. Very low rates of solvent evaporation yielded nanoparticle loaded block copolymer nanoparticles with intricate internal geometries.
요약	Our studies show that the emulsion and solvent evaporation process is a highly tunable and robust process that can afford access to micelles with interesting morphologies and superior functionality.
요약	References: 1. Zhu, J.
일반주제명	Chemical engineering.
언어	영어
기본자료 저록	Dissertation Abstracts International79-12B(E). Dissertation Abstract International
대출바로가기	http://www.riss.kr/pdu/ddodLink.do?id=T15000335