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Biomimetic Electrospun Fibers for Cancer Cell Migration, Chemotaxis, and Anti-Metastatic Drug Testing
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Nelson, Mark Tyler. |
| 단체저자명 | The Ohio State University. Biomedical Engineering. |
| 서명/저자사항 | Biomimetic Electrospun Fibers for Cancer Cell Migration, Chemotaxis, and Anti-Metastatic Drug Testing. |
| 발행사항 | [S.l.] : The Ohio State University., 2015 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2015 |
| 형태사항 | 347 p. |
| 소장본 주기 | School code: 0168. |
| ISBN | 9780438097643 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: John Lannutti. |
| 요약 | Electrospun fibers are currently utilized in a wide range of biomedical and commercial applications. The unique microstructure and morphology of electrospun nanofibers produce nanoscale inter-fiber porosity and large surface areas that promote c |
| 요약 | In addition, electrospun fiber microstructure and morphology closely resembles and mimics the extracellular matrix (ECM) of human tissues and tumors. In my work, supercritical carbon dioxide (SCCO2) mediated infusion of small molecules |
| 요약 | Supercritical fluids present an approach capable of enhancing the chemical activity of composite tissue engineering scaffolds. Previous attempts to embed test compounds into electrospun polycaprolactone (PCL) alone at pressures above 6.20 MPa an |
| 요약 | High-throughput in vitro tools allowing rapid, accurate, and novel anti-metastatic drug screening are grossly overdue. Conversely, aligned nanofiber constitutes a prominent topographic component of the late-stage tumor margin extracellular matri |
| 요약 | Further investigation in the cellular and genetic mechanisms that enhance the ability of tumor cells to sense topographical and chemotactic cues will aid in determining novel targets for future anti-metastatic drug development. The reported work |
| 일반주제명 | Biomedical engineering. Cellular biology. Materials science. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15000277 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024974 | 610 | 가야대학교// | 대출가능 |
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