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Part I. the Rational Design, Synthesis, and Evaluation of Second Generation Class II HMG-COA Reductase Inhibitors Part II. Studies Directed Toward the On-Resin Preparation of C-Terminal Modified and Cyclic Peptides
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Hostetler, Matthew A. |
| 단체저자명 | Purdue University. Chemistry. |
| 서명/저자사항 | Part I. the Rational Design, Synthesis, and Evaluation of Second Generation Class II HMG-COA Reductase Inhibitors Part II. Studies Directed Toward the On-Resin Preparation of C-Terminal Modified and Cyclic Peptides. |
| 발행사항 | [S.l.] : Purdue University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 381 p. |
| 소장본 주기 | School code: 0183. |
| ISBN | 9780438361652 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Mark A. Lipton. |
| 요약 | The first part of this dissertation involves the rational design, synthesis and biological evaluation of small molecules targeting Class II HMGR. Inhibitors of this generation were designed based on information derived from the crystal structure |
| 요약 | The second part of this dissertation summarizes our efforts to contribute new methods for the preparation of C-terminal modified and cyclic peptides on the solid-phase using the backbone amide linker (BAL) approach. To this end, an improved one- |
| 일반주제명 | Organic chemistry. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999963 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024698 | DP 547 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출불가(별치) |
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