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Understanding (p)ppGpp-mediated Mechanisms of Persistence and Stress Survival in Bacillus subtilis
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Barra, Jessica Tse. |
| 단체저자명 | The University of Wisconsin - Madison. Microbiology ALS. |
| 서명/저자사항 | Understanding (p)ppGpp-mediated Mechanisms of Persistence and Stress Survival in Bacillus subtilis. |
| 발행사항 | [S.l.] : The University of Wisconsin - Madison., 2017 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2017 |
| 형태사항 | 261 p. |
| 소장본 주기 | School code: 0262. |
| ISBN | 9780438159679 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Jue D. Wang. |
| 요약 | During amino acid starvation, the Gram-positive bacterium Bacillus subtilis, produces a molecule called (p)ppGpp, a nucleotide derived from GTP or GDP and ATP. This molecule is produced by almost all bacteria but its effects are best characteriz |
| 요약 | We examined the role of (p)ppGpp in mediating persistence, the ability of a subpopulation of bacteria to survive antibiotics for a prolonged period of time. We demonstrate that (p)ppGpp is one mechanism of persister formation and is necessary an |
| 요약 | (p)ppGpp and GTP-dependent mechanisms protect cells against bacteriostatic antibiotics. We treated wild type and (p)ppGpp0 cells with chloramphenicol and saw that (p)ppGpp0 cells lose viability. Interestingly, RelA was the primary (p)ppGpp synth |
| 요약 | In this work, we comprehensively examined the role of (p)ppGpp in mediating stress survival in persistence. |
| 일반주제명 | Microbiology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14996781 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024402 | 576 | 가야대학교// | 대출가능 |
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