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Regulation of Glucose Homeostasis by FGF21
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Bon Durant, Lucas Donald. |
| 단체저자명 | The University of Iowa. Molecular & Cell Biology. |
| 서명/저자사항 | Regulation of Glucose Homeostasis by FGF21. |
| 발행사항 | [S.l.] : The University of Iowa., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 122 p. |
| 소장본 주기 | School code: 0096. |
| ISBN | 9780438151482 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Matthew J. Potthoff. |
| 요약 | Fibroblast Growth Factor 21 (FGF21) is an endocrine hormone derived from the liver that exerts pleiotropic effects on the body to maintain overall metabolic homeostasis. During the past decade, there has been an enormous effort to understand the |
| 요약 | To address the first goal, we used different FGF21 genetic knockout mouse models to determine if loss of FGF21 would affect macronutrient preference. We found that loss of FGF21 led to an increase in simple sugar intake whereas this had no effec |
| 요약 | To address the pharmacological actions of FGF21, we generated an adipose-specific KLB KO mouse using mice that express Cre-recombinase under the adiponectin promoter. These mice lack the co-receptor for FGF21 in adipose tissue and are a more rel |
| 일반주제명 | Pharmacology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14996745 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024366 | 615 | 가야대학교// | 대출가능 |
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