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The Effects of Hepatitis C Infection, Treatment, and Population Interventions on All-Cause Mortality Among People Living with HIV
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Breskin, Alexander Samuel. |
| 단체저자명 | The University of North Carolina at Chapel Hill. Epidemiology. |
| 서명/저자사항 | The Effects of Hepatitis C Infection, Treatment, and Population Interventions on All-Cause Mortality Among People Living with HIV. |
| 발행사항 | [S.l.] : The University of North Carolina at Chapel Hill., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 180 p. |
| 소장본 주기 | School code: 0153. |
| ISBN | 9780438065727 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Daniel Westreich. |
| 요약 | Approximately 25% of people living with HIV (PLWH) in the United States are co-infected with hepatitis C virus (HCV), which, if left untreated, causes mortality through decompensated cirrhosis and hepatocellular carcinoma. Direct-acting antivira |
| 요약 | Using data from 3,056 PLWH in the Women's Interagency HIV Study and Multicenter AIDS Cohort Study from 1994 to 2015, we used the parametric g-formula to estimate the effects of HCV infection and DAA treatment on 10-year all-cause mortality. We a |
| 요약 | The estimated 10-year mortality risk difference (RD) for HCV infection was 4.3% (95% CI: 0.4%, 8.9%). The RD for DAA treatment was -3.7% (95%CI: -9.1%, 0.6%). The RD for treating those with HIV suppression and severe fibrosis or cirrhosis was -1 |
| 요약 | These results show that HCV is a major cause of mortality among PLWH, and that DAA treatment is effective at reducing mortality in this population. They also suggest that common DAA access criteria may be suboptimal and expanding access to these |
| 일반주제명 | Epidemiology. Biostatistics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14998499 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024071 | 614.4 | 가야대학교// | 대출가능 |
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