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Positive and Negative Regulation of Cell Fusion in Saccharomyces cerevisiae
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Hall, Allison Elizabeth. |
| 단체저자명 | Princeton University. Molecular Biology. |
| 서명/저자사항 | Positive and Negative Regulation of Cell Fusion in Saccharomyces cerevisiae. |
| 발행사항 | [S.l.] : Princeton University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 166 p. |
| 소장본 주기 | School code: 0181. |
| ISBN | 9780438048584 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Mark D. Rose. |
| 요약 | Cell fusion is ubiquitous in eukaryotic organisms. Saccharomyces cerevisiae cells fuse during mating |
| 요약 | The highly conserved Rho-GTPase, Cdc42p, functions in polarized growth during pheromone response and prezygote formation. Cdc42p binds the heterodimer amphiphysin, Fus2p/Rvs161p, facilitating cell wall degradation. Cdc42p is recruited to a focus |
| 요약 | A hyperactive component of the cell wall integrity (CWI) pathway, Pkc1p (PKC1*), causes a cell fusion defect, suggesting a negative regulatory role in cell fusion. The cell wall is monitored by five transmembrane proteins, Wsc1-3p, Mid2p, and Mt |
| 요약 | In the course of these studies, we found that WSC1 has a zygote/diploid specific role differing from the role of MID2. Diploids die at a high rate without WSC1, due to cell lysis during budding. These differences underscore the distinct function |
| 일반주제명 | Molecular biology. Cellular biology. Genetics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14998486 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024062 | 574 | 가야대학교// | 대출가능 |
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