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Systems Genetics Approach to Defining Genetic and MicroRNA Association with Diet-Associated Atherosclerosis

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자료유형E-Book
개인저자Coffey, Alisha Renee.
단체저자명The University of North Carolina at Chapel Hill. Genetics and Molecular Biology.
서명/저자사항Systems Genetics Approach to Defining Genetic and MicroRNA Association with Diet-Associated Atherosclerosis.
발행사항[S.l.] : The University of North Carolina at Chapel Hill., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항150 p.
소장본 주기School code: 0153.
ISBN9780438033498
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: Brian J. Bennett
요약Atherosclerosis is a progressive condition that can develop over the course of decades, and eventually lead to cardiovascular disease, which is the leading cause of death in the world. Metabolic imbalance in the liver can cause dyslipidemia (abn
요약MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene expression in various biological and pathological processes, and have been shown to be dysregulated in atherosclerosis. Most previous mouse studies of miRNAs in
요약The majority of previous studies on the cardiovascular disease risk factor and liver metabolite TMAO focus on its regulation by the gut microbiota as well as some host liver enzymes. However, there have been very few studies to investigate the e
요약The findings from this body of work contribute to the field by addressing two major knowledge gaps, and warrant further study and validation in the context of atherosclerosis.
일반주제명Genetics.
Molecular biology.
언어영어
기본자료 저록Dissertation Abstracts International79-10B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14996889

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