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The Spliceosome E Complex Fine-Tunes 5' Splice Site Interactions
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Larson, Joshua Donald. |
| 단체저자명 | The University of Wisconsin - Madison. Biophysics. |
| 서명/저자사항 | The Spliceosome E Complex Fine-Tunes 5' Splice Site Interactions. |
| 발행사항 | [S.l.] : The University of Wisconsin - Madison., 2017 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2017 |
| 형태사항 | 228 p. |
| 소장본 주기 | School code: 0262. |
| ISBN | 9780438373877 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Aaron A. Hoskins. |
| 요약 | Removal of introns from pre-mRNAs by the spliceosome is an essential cellular process in eukaryotes. The spliceosome is a macromolecular machine composed of five small nuclear ribonuclearprotein particles (snRNPs). These snRNPs assemble on intr |
| 요약 | To study the dynamics of E complex formation, I designed a novel microscope platform and constructed a multi-wavelength micromirror total internal reflectance microscope capable of monitoring the composition and dynamics of complex macromolecula |
| 요약 | The results presented in this thesis reveal that the majority of E complex forms transiently via a branched pathway with little commitment of a particular pre-mRNA or 5' SS/BS pair to subsequent splicing. Despite transient E complex formation, U |
| 일반주제명 | Biophysics. Biochemistry. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14996581 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028915 | 574.191 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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