자료유형 | E-Book |
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개인저자 | Wal, Megha. |
단체저자명 | The Pennsylvania State University. Biochemistry, Microbiology and Molecular Biology. |
서명/저자사항 | Mechanism for Nucleosome Organization Reconstituted Across a Eukaryotic Genome. |
발행사항 | [S.l.] : The Pennsylvania State University., 2016 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2016 |
형태사항 | 200 p. |
소장본 주기 | School code: 0176. |
ISBN | 9780438136038 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
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요약 | The eukaryotic genome is packaged into chromatin, which renders the DNA inaccessible to DNA-templated cellular processes. These include DNA replication, repair, recombination and transcription. Packaging of the genome into chromatin is achieved |
요약 | While these studies have provided a basic framework to study the determinants of nucleosome positioning, a lot of questions still remain unanswered. We do not have a deep understanding about role of particular factors in different aspects of nuc |
요약 | Specifically we show how nucleosome positioning is reconstituted in a step-wise manner using DNA, histones, chromatin remodelers and sequence-specific factors as minimal constituents. In stage 1, DNA sequence features determine NFR formation and |
요약 | Taken together, the work in this thesis has provided advancement into the role of chromatin remodelers as major players in nucleosome organization. We provide some initial evidence for remodeler mechanisms in nucleosome restructuring and a minim |
일반주제명 | Biochemistry. Bioinformatics. Molecular biology. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15000735 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
---|---|---|---|---|---|---|---|---|
1 | WE00028195 | 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |