자료유형 | E-Book |
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개인저자 | Chun, Sang Young. |
단체저자명 | University of Michigan. Bioinformatics. |
서명/저자사항 | Development and Application of Next-Generation Sequencing Methods to Profile Cellular Translational Dynamics. |
발행사항 | [S.l.] : University of Michigan., 2018 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
형태사항 | 166 p. |
소장본 주기 | School code: 0127. |
ISBN | 9780438126879 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Ryan Edward Mills. |
요약 | The transmission of genetic information from the transcription of DNA to RNA and the subsequent translation of RNA into protein is often abstracted into a linear process. However, as methods and technologies to measure the genomic, transcriptomi |
요약 | In the first chapter, I survey the development and application of next-generation sequencing methods for the profiling and computational analysis of translation and translational dynamics. In the second chapter of this thesis, I present SPECtre, |
요약 | In the third chapter, I describe the application of SPECtre to identify the translation of upstream-initiated open-reading frames that may regulate differentiation in a neuron-like cell model. uORFs are transcripts that result from the initiatio |
요약 | Finally, in the fourth chapter, I outline a strategy using our coherence-based translational scoring algorithm to profile ribosomal engagement over chimeric gene fusion breakpoints in prostate cancer. Here, known breakpoints from current annotat |
일반주제명 | Bioinformatics. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15000576 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
---|---|---|---|---|---|---|---|---|
1 | WE00028152 | 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |