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Polyunsaturated Fatty Acids and Early-Life Cardiometabolic Disease Risk

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자료유형	E-Book
개인저자	Flannagan, Kerry Susan.
단체저자명	University of Michigan. Epidemiological Science.
서명/저자사항	Polyunsaturated Fatty Acids and Early-Life Cardiometabolic Disease Risk.
발행사항	[S.l.] : University of Michigan., 2018
발행사항	Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항	199 p.
소장본 주기	School code: 0127.
ISBN	9780438126787
일반주기	Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. Adviser: Eduardo Villamor.
요약	Background: Polyunsaturated fatty acid (PUFA) intake is low throughout Latin America, but sociodemographic patterning and dietary sources of PUFA status in the region are poorly characterized. PUFA may be related to the development of early-life
요약	Objectives: To identify sociodemographic, anthropometric, and dietary correlates of PUFA status in Mesoamerica (aim 1), and to examine the relations of n-3 and n-6 PUFA with metabolic syndrome (MetS) (aim 2) and development of adiposity in child
요약	Methods: Aims 1 and 2 were completed using data from the Nine Mesoamerican Countries Metabolic Syndrome (NiMeCoMeS) study, a cross-sectional investigation of school-age children and their parents from the capital cities of Guatemala, Honduras, E
요약	In aim 1, we assessed correlates of adipose tissue PUFA biomarkers by estimating percent mean differences in each PUFA between levels of predictors using multivariable-adjusted linear regression models.
요약	In aim 2, we examined associations between PUFA and MetS in parents, and between PUFA and a continuous metabolic risk score in children. We estimated prevalence ratios of MetS in adults and mean differences in metabolic score in children across
요약	Aim 3 was conducted in the context of a cohort of children from Santiago, Chile who were recruited in infancy and followed through adolescence. PUFA were quantified in serum at 5 and 10 y of age. Body mass index (BMI) was measured at 5, 10, and
요약	Results: Country of origin was the strongest predictor of all essential and long-chain PUFA biomarkers. The type of cooking oil used in the home was the strongest dietary correlate of PUFA status. Among adults, MetS prevalence was inversely asso
요약	Conclusions and significance: PUFA status within Latin America is heterogeneous and is related to the type of vegetable oil used for cooking. ALA is inversely associated with MetS among adults but long-chain n-3 PUFA do not appear to be protecti
일반주제명	Epidemiology.
언어	영어
기본자료 저록	Dissertation Abstracts International79-12B(E). Dissertation Abstract International
대출바로가기	http://www.riss.kr/pdu/ddodLink.do?id=T15000568