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Integrating Genetics into Population-based Studies

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자료유형E-Book
개인저자Tai, Caroline G.
단체저자명University of California, San Francisco. Epidemiology and Translational Science.
서명/저자사항Integrating Genetics into Population-based Studies.
발행사항[S.l.] : University of California, San Francisco., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항104 p.
소장본 주기School code: 0034.
ISBN9780438250161
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: John S. Witte.
요약As genotyping has become more affordable, there has been a growing effort to leverage genetic data to improve our understanding of the determinants of disease at the population level. New challenges arise with more widespread use of genetic data
요약This dissertation was comprised of three projects that showcase important topics for epidemiologists to consider when using genetic data. These include developing genetic risk scores, determining the analysis method most suitable for the availab
요약The first chapter explores differential genetic susceptibility between aggressive and non-aggressive prostate cancer and whether these differences can be used to develop a polygenic risk score for disease aggressiveness. This study was conducted
요약The lessons learned from this dissertation provide evidence that genetic data allows for exploration of inherited susceptibilities that can influence risk of disease but care must be taken to understand which groups of individuals should be comp
일반주제명Epidemiology.
Genetics.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14998678

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