| LDR | | 02348nmm uu200433 4500 |
| 001 | | 000000333729 |
| 005 | | 20240805174430 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438250161 |
| 035 | |
▼a (MiAaPQ)AAI10824588 |
| 035 | |
▼a (MiAaPQ)ucsf:11617 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 614.4 |
| 100 | 1 |
▼a Tai, Caroline G. |
| 245 | 10 |
▼a Integrating Genetics into Population-based Studies. |
| 260 | |
▼a [S.l.] :
▼b University of California, San Francisco.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 104 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: John S. Witte. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of California, San Francisco, 2018. |
| 520 | |
▼a As genotyping has become more affordable, there has been a growing effort to leverage genetic data to improve our understanding of the determinants of disease at the population level. New challenges arise with more widespread use of genetic data |
| 520 | |
▼a This dissertation was comprised of three projects that showcase important topics for epidemiologists to consider when using genetic data. These include developing genetic risk scores, determining the analysis method most suitable for the availab |
| 520 | |
▼a The first chapter explores differential genetic susceptibility between aggressive and non-aggressive prostate cancer and whether these differences can be used to develop a polygenic risk score for disease aggressiveness. This study was conducted |
| 520 | |
▼a The lessons learned from this dissertation provide evidence that genetic data allows for exploration of inherited susceptibilities that can influence risk of disease but care must be taken to understand which groups of individuals should be comp |
| 590 | |
▼a School code: 0034. |
| 650 | 4 |
▼a Epidemiology. |
| 650 | 4 |
▼a Genetics. |
| 690 | |
▼a 0766 |
| 690 | |
▼a 0369 |
| 710 | 20 |
▼a University of California, San Francisco.
▼b Epidemiology and Translational Science. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0034 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998678
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |