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Rapid Encoding of Odor Identity via a Primacy Code

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자료유형	E-Book
개인저자	Wilson, Christopher D.
단체저자명	New York University. Basic Medical Science.
서명/저자사항	Rapid Encoding of Odor Identity via a Primacy Code.
발행사항	[S.l.] : New York University., 2018
발행사항	Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항	148 p.
소장본 주기	School code: 0146.
ISBN	9780438170940
일반주기	Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. Adviser: Dmitry Rinberg.
요약	Stimulus variability presents a computational challenge for sensory systems. In the olfactory system, shifts in odor concentration represent a significant source of variability. This thesis examines a potential computational principle underlying
요약	Primacy coding represents odor identity in only a small number of maximally sensitive sensors for a given odor. By isolating these primary features from the overall population of responses, it has been proposed that a large degree of invariance
요약	We hypothesize that primary set responds with the lowest latency, and that the olfactory system uses time to recover this invariant set from the overall pattern of activity. By using solely a small number of earliest responses in a sniff, the sy
요약	To test whether early odor-evoked activity is sufficient for odor identification, we employed a novel behavioral paradigm named "optogenetic masking". Mice were trained to discriminate between odors across a range of concentrations. On a small n
요약	To study whether early odor-evoked neural activity is actually a good source of odor identity information, we employed extracellular electrophysiology and advanced olfactometery. In recording from putative mitral/tufted cells in the olfactory bu
요약	Finally, I undertook an exploratory project to determine the transfer function of the olfactory bulb using patterned optogenetic stimulation. Using this technology, we hope to establish an input-output model of the OB that will allow us to evalu
일반주제명	Neurosciences.
언어	영어
기본자료 저록	Dissertation Abstracts International79-12B(E). Dissertation Abstract International
대출바로가기	http://www.riss.kr/pdu/ddodLink.do?id=T14997087