자료유형 | E-Book |
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개인저자 | Ventrella, Rosa. |
단체저자명 | Northwestern University. Dermatology. |
서명/저자사항 | Molecular Organization of EphA2 Cell-Cell Communication Complexes in Human Keratinocytes. |
발행사항 | [S.l.] : Northwestern University., 2018 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
형태사항 | 183 p. |
소장본 주기 | School code: 0163. |
ISBN | 9780438116092 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Spiro Getsios. |
요약 | Erythropoietin-producing human hepatocellular (Eph) receptors and their corresponding ephrin ligands are asymmetrically expressed at cell-cell contacts allowing for bidirectional signaling with forward signaling through the receptor expressing c |
요약 | Ephrin-A1 contains a glycosylphosphatidylinositol (GPI)-linked tail, which targets this ligand to specific membrane microdomains known as lipid rafts. Lipid raft domains are important for regulating the distribution of membrane proteins and are |
요약 | In order to address these hypotheses, we used a combination of biochemical and imaging approaches to study the molecular organization of ephrin-A1 and EphA2 signaling complexes in a primary human keratinocyte culture model. We provide evidence t |
요약 | Collectively, these studies highlight a key role for the EphA2 TMD and its association with lipid rafts in modulating downstream signaling. Our data highlight the importance of EphA2 localization to lipid raft domains at cell-cell contacts in co |
일반주제명 | Cellular biology. Molecular biology. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14997740 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
---|---|---|---|---|---|---|---|---|
1 | WE00027337 | 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |