자료유형 | E-Book |
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개인저자 | Chambers, Gregory D. |
단체저자명 | The University of New Mexico. Nuclear Engineering. |
서명/저자사항 | Development of a Positron-Emitting Surrogate Microsphere for Image-Based Dosimetry in Yttrium-90 Radioembolization Therapy. |
발행사항 | [S.l.] : The University of New Mexico., 2018 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
형태사항 | 208 p. |
소장본 주기 | School code: 0142. |
ISBN | 9780438227170 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Reed Selwyn. |
요약 | Radioembolization of liver tumors using yttrium-90 (Y-90) labeled microspheres is a proven method of treatment. The primary decay mode of Y-90 is beta-minus decay. The electrons produced during decay deliver a cytotoxic radiation dose in a local |
요약 | This study was performed to create a positron-emitting surrogate microsphere that was close in size and shape to the Y-90 microspheres. Positron emission tomography (PET) is superior to SPECT for activity quantification. Fluorine-18 (F-18) was c |
요약 | Aim 1: To develop surrogate PET microsphere. This included radiolabeling, stability testing in vitro and stability testing in an animal. |
요약 | Aim 2: To develop a computational technique to perform dosimetry with the surrogate microsphere. PET images of the surrogate radionuclide were imported into a Monte Carlo program. PET images were used to simulate the distribution of the Y-90 mic |
일반주제명 | Medicine. Nuclear physics and radiation. Medical imaging. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14997554 |