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Developing Tools for Paper-based Cultures to Interrogate Oxygen's Role in Cancer Progression

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개인저자Boyce, Matthew William.
단체저자명The University of North Carolina at Chapel Hill. Chemistry.
서명/저자사항Developing Tools for Paper-based Cultures to Interrogate Oxygen's Role in Cancer Progression.
발행사항[S.l.] : The University of North Carolina at Chapel Hill., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항153 p.
소장본 주기School code: 0153.
ISBN9780438033986
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: Matthew R. Lockett
요약Oxygen plays a direct role in controlling cellular phenotype and invasiveness through hypoxia-inducible transcription factors. These factors, which induce signaling pathways under low-oxygen tensions (i.e., hypoxia), are involved with the mainte
요약Paper-based cultures are an emerging platform capable of generating thick, tissue-like constructs of cells by simply stacking together cell-laden paper scaffolds. Controlling the diffusion of medium into these cultures results in the formation o
요약In this work, PBCs were used to explore the relationship between oxygen gradients and cancer chemosensitivity. Quantification of oxygen gradients within PBCs was performed using luminescent oxygen-sensors. Development and characterization of the
일반주제명Analytical chemistry.
언어영어
기본자료 저록Dissertation Abstracts International79-10B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14997284

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