LDR | | 00000nmm u2200205 4500 |
001 | | 000000332376 |
005 | | 20241202151620 |
008 | | 181129s2018 ||| | | | eng d |
020 | |
▼a 9780438033986 |
035 | |
▼a (MiAaPQ)AAI10784783 |
035 | |
▼a (MiAaPQ)unc:17561 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
049 | 1 |
▼f DP |
082 | 0 |
▼a 543 |
100 | 1 |
▼a Boyce, Matthew William. |
245 | 10 |
▼a Developing Tools for Paper-based Cultures to Interrogate Oxygen's Role in Cancer Progression. |
260 | |
▼a [S.l.] :
▼b The University of North Carolina at Chapel Hill.,
▼c 2018 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
300 | |
▼a 153 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
500 | |
▼a Advisers: Matthew R. Lockett |
502 | 1 |
▼a Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2018. |
520 | |
▼a Oxygen plays a direct role in controlling cellular phenotype and invasiveness through hypoxia-inducible transcription factors. These factors, which induce signaling pathways under low-oxygen tensions (i.e., hypoxia), are involved with the mainte |
520 | |
▼a Paper-based cultures are an emerging platform capable of generating thick, tissue-like constructs of cells by simply stacking together cell-laden paper scaffolds. Controlling the diffusion of medium into these cultures results in the formation o |
520 | |
▼a In this work, PBCs were used to explore the relationship between oxygen gradients and cancer chemosensitivity. Quantification of oxygen gradients within PBCs was performed using luminescent oxygen-sensors. Development and characterization of the |
590 | |
▼a School code: 0153. |
650 | 4 |
▼a Analytical chemistry. |
690 | |
▼a 0486 |
710 | 20 |
▼a The University of North Carolina at Chapel Hill.
▼b Chemistry. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0153 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14997284
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자
▼b 관리자 |