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Defining Mechanisms of Disease Initiation through Analysis of Helicobacter pylori Interactions with Gastric Microbial Communities and the Host

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개인저자Gall, Alevtina A.
단체저자명University of Washington. Molecular and Cellular Biology.
서명/저자사항Defining Mechanisms of Disease Initiation through Analysis of Helicobacter pylori Interactions with Gastric Microbial Communities and the Host.
발행사항[S.l.] : University of Washington., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항155 p.
소장본 주기School code: 0250.
ISBN9780438175310
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Nina R. Salama.
요약Helicobacter pylori is an exceptionally prevalent bacterial pathogen that colonizes the human stomach where it can cause inflammation, and in some cases lead to gastric ulcers and cancer. H. pylori infection also seems to protect against develo
요약H. pylori may be modulating esophageal adenocarcinoma risk through its interactions with members of the upper gastrointestinal microbial communities. Before that hypothesis can be tested, a comprehensive survey of which microbial community membe
요약H. pylori is recognized by both the innate and adaptive immune system, but this rarely results in bacterial clearance. H. pylori establishes chronic colonization, in part, by evading numerous host defense strategies. However, H. pylori also seem
요약The discrepancy between our in vitro and in vivo findings motivated us to develop a better gastric epithelial cell model to study innate immune signaling pathways involved in H. pylori detection. Using mouse and human gastric tissues, we select
일반주제명Microbiology.
Immunology.
Cellular biology.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14998987

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