| LDR | | 02450nmm uu200457 4500 |
| 001 | | 000000331829 |
| 005 | | 20240805165444 |
| 008 | | 181129s2018 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438175310 |
| 035 | |
▼a (MiAaPQ)AAI10827148 |
| 035 | |
▼a (MiAaPQ)washington:18632 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 576 |
| 100 | 1 |
▼a Gall, Alevtina A. |
| 245 | 10 |
▼a Defining Mechanisms of Disease Initiation through Analysis of Helicobacter pylori Interactions with Gastric Microbial Communities and the Host. |
| 260 | |
▼a [S.l.] :
▼b University of Washington.,
▼c 2018 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
| 300 | |
▼a 155 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Adviser: Nina R. Salama. |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Washington, 2018. |
| 520 | |
▼a Helicobacter pylori is an exceptionally prevalent bacterial pathogen that colonizes the human stomach where it can cause inflammation, and in some cases lead to gastric ulcers and cancer. H. pylori infection also seems to protect against develo |
| 520 | |
▼a H. pylori may be modulating esophageal adenocarcinoma risk through its interactions with members of the upper gastrointestinal microbial communities. Before that hypothesis can be tested, a comprehensive survey of which microbial community membe |
| 520 | |
▼a H. pylori is recognized by both the innate and adaptive immune system, but this rarely results in bacterial clearance. H. pylori establishes chronic colonization, in part, by evading numerous host defense strategies. However, H. pylori also seem |
| 520 | |
▼a The discrepancy between our in vitro and in vivo findings motivated us to develop a better gastric epithelial cell model to study innate immune signaling pathways involved in H. pylori detection. Using mouse and human gastric tissues, we select |
| 590 | |
▼a School code: 0250. |
| 650 | 4 |
▼a Microbiology. |
| 650 | 4 |
▼a Immunology. |
| 650 | 4 |
▼a Cellular biology. |
| 690 | |
▼a 0410 |
| 690 | |
▼a 0982 |
| 690 | |
▼a 0379 |
| 710 | 20 |
▼a University of Washington.
▼b Molecular and Cellular Biology. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0250 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2018 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14998987
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |