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Functional Mapping of the Components of the E. coli Translational Machinery

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개인저자Mohapatra, Sonisilpa.
단체저자명The University of Wisconsin - Madison. Chemistry.
서명/저자사항Functional Mapping of the Components of the E. coli Translational Machinery.
발행사항[S.l.] : The University of Wisconsin - Madison., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항210 p.
소장본 주기School code: 0262.
ISBN9780438269071
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: James Carl Weisshaar.
요약Bacterial cells generally lack membrane-bound organelles. Therefore, traditionally they were viewed as bags of freely diffusing macromolecules devoid of any internal organization. The development in imaging techniques in the last two decades has
요약Most cellular processes are regulated by complex networks of intermolecular interactions. A systematic study quantifying the correlation in spatial organization of various biomolecules might help to unravel their underlying interactions. A posit
요약Translation is one of the most important cellular process. Ribosomes are the central component of translation engaged in protein synthesis from mRNA. Optimal usage of ribosomes is dependent on their spatial organization. In this dissertation, th
요약In rapidly growing E. coli and B. subtilis, strong nucleoid -- ribosome segregation is observed. The picture of spatial organization in slowly growing C. crescentus is however completely different. The effect of growth rate on the segregation of
요약In cells, the translation elongation is discontinuous, often suffering from periods of pauses. The cells have mechanisms to alleviate these pauses, irrespective of the reason for pausing. EF-P is a translation factor that alleviates pausing duri
요약Overall, the reported works explore the synergism of interactions between different components of translation and their spatiotemporal organization. The famous biologist Jacques Monod noted "What was true for the E. coli would be true for the e
일반주제명Physical chemistry.
Biophysics.
Chemistry.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T15000877

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