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Identifying Genetic Factors Involved in Aging and Neurodegeneration
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Macke, Erica Lynn. |
| 단체저자명 | The University of Wisconsin - Madison. Genetics. |
| 서명/저자사항 | Identifying Genetic Factors Involved in Aging and Neurodegeneration. |
| 발행사항 | [S.l.] : The University of Wisconsin - Madison., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 174 p. |
| 소장본 주기 | School code: 0262. |
| ISBN | 9780438200944 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Akihiro Ikeda. |
| 요약 | The broad objective of my research is to understand the onset and progression of aging and age-related diseases. By studying the normal aging process, as well as mutants exhibiting abnormal aging phenotypes, we can elucidate the mechanisms invol |
| 요약 | First, I utilized two inbred mouse lines that show differences in the rate of retinal aging in order to elucidate the molecular mechanisms of the aging process. It has been shown that an inbred strain, A/J, is susceptible to age-dependent retina |
| 요약 | Next, we found that a spontaneous mutant mouse line, small with kinky tail (skt), exhibits accelerated aging phenotypes. We have identified age-dependent retinal abnormalities including retinal degeneration, hippocampal neurodegeneration, increa |
| 일반주제명 | Genetics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999726 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00025573 | 575 | 가야대학교// | 대출가능 |
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