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Methylome Analysis: From Computation Workflow Development to Implementation in a Breast Cancer Prevention Trial

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자료유형E-Book
개인저자Frankhouser, David E.
단체저자명The Ohio State University. Biomedical Sciences.
서명/저자사항Methylome Analysis: From Computation Workflow Development to Implementation in a Breast Cancer Prevention Trial.
발행사항[S.l.] : The Ohio State University., 2017
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2017
형태사항127 p.
소장본 주기School code: 0168.
ISBN9780438097940
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Advisers: Lisa Yee
요약Cancer research is rapidly advancing toward more personalized treatments and diagnostics. The major driving force of this advancement are the technological developments of sequencing which has resulted in greatly reduced costs. The democratizati
요약MethylCap-seq is an approach that uses a protein that binds to DNAm to capture methylated DNA fragments. A region with a large number of captured fragments is interpreted as having high DNAm. Therefore, quantification is based on the number of f
요약Unlike MethylCap-seq, BS-seq provides DNAm quantification at nucleotide resolution and is considered the gold-standard of DNAm sequencing assays. We utilized BS-seq to assess DNAm for an on-going clinical trial that aims to investigate the effic
일반주제명Bioinformatics.
Biomedical engineering.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T15000290

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