| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000330655 |
| 005 | | 20241104115455 |
| 008 | | 181129s2017 ||| | | | eng d |
| 020 | |
▼a 9780438097940 |
| 035 | |
▼a (MiAaPQ)AAI10901852 |
| 035 | |
▼a (MiAaPQ)OhioLINK:osu1512052081030923 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Frankhouser, David E. |
| 245 | 10 |
▼a Methylome Analysis: From Computation Workflow Development to Implementation in a Breast Cancer Prevention Trial. |
| 260 | |
▼a [S.l.] :
▼b The Ohio State University.,
▼c 2017 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2017 |
| 300 | |
▼a 127 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B. |
| 500 | |
▼a Advisers: Lisa Yee |
| 502 | 1 |
▼a Thesis (Ph.D.)--The Ohio State University, 2017. |
| 520 | |
▼a Cancer research is rapidly advancing toward more personalized treatments and diagnostics. The major driving force of this advancement are the technological developments of sequencing which has resulted in greatly reduced costs. The democratizati |
| 520 | |
▼a MethylCap-seq is an approach that uses a protein that binds to DNAm to capture methylated DNA fragments. A region with a large number of captured fragments is interpreted as having high DNAm. Therefore, quantification is based on the number of f |
| 520 | |
▼a Unlike MethylCap-seq, BS-seq provides DNAm quantification at nucleotide resolution and is considered the gold-standard of DNAm sequencing assays. We utilized BS-seq to assess DNAm for an on-going clinical trial that aims to investigate the effic |
| 590 | |
▼a School code: 0168. |
| 650 | 4 |
▼a Bioinformatics. |
| 650 | 4 |
▼a Biomedical engineering. |
| 690 | |
▼a 0715 |
| 690 | |
▼a 0541 |
| 710 | 20 |
▼a The Ohio State University.
▼b Biomedical Sciences. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-12B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0168 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2017 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15000290
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 관리자 |