자료유형 | E-Book |
---|---|
개인저자 | Dey, Kushal K. |
단체저자명 | The University of Chicago. Statistics. |
서명/저자사항 | Model Based Visualization of Structure in Biological Data. |
발행사항 | [S.l.] : The University of Chicago., 2018 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
형태사항 | 130 p. |
소장본 주기 | School code: 0330. |
ISBN | 9780438371170 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Matthew Stephens. |
요약 | Biological Data comes in varied forms and the scale of the data is typically large, which often necessitates distinct modeling frameworks and tools to process, analyze and visually summarize the data. An overarching theme of this doctoral thesis |
요약 | The second chapter of this thesis extends the concept of a mixed membership model, popularly known as ADMIXTURE model in population genetics and topic model in Natural Language Processing (NLP), to the context of RNA-sequencing read expression |
요약 | The third chapter extends similar mixed membership models to analyzing DNA damage patterns in ancient DNA (aDNA) samples, and explore and jointly summarize multiple aDNA samples together with modern samples. Applied to a combined data of modern |
요약 | The visual summary of DNA damage patterns, depicted above, includes a version of logo plot that highlights enrichment and depletion of damage features with respect to a background level of mismatch features computed from modern individuals. We c |
요약 | In the fifth chapter, we propose an adaptive method for shrinking correlation matrices that leads to a parsimonious representation of the underlying association structure between variables. This method is flexible in handling data matrices with |
일반주제명 | Biostatistics. Bioinformatics. Genetics. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999898 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
---|---|---|---|---|---|---|---|---|
1 | WE00024633 | DP 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출불가(별치) |