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Modulation of the Arrhythmia Substrate in Cardiovascular Disease
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Long, Victor Paul, III. |
| 단체저자명 | The Ohio State University. Pharmacy. |
| 서명/저자사항 | Modulation of the Arrhythmia Substrate in Cardiovascular Disease. |
| 발행사항 | [S.l.] : The Ohio State University., 2016 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2016 |
| 형태사항 | 155 p. |
| 소장본 주기 | School code: 0168. |
| ISBN | 9780438091207 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Cynthia Carnes. |
| 요약 | Heart failure remains a leading cause of morbidity and mortality in the United States. Many of the deaths attributed to heart failure are sudden, presumably due to lethal arrhythmia. It is a combination of structural and electrical remodeling wi |
| 요약 | We found that heart failure duration is very important in the progressive reduction of the repolarization reserve of K+ currents in the ventricle. Our results differ from other models, as we were able to identify IKr reduction in chronic heart f |
| 요약 | Our chronic heart failure model was also used to investigate the role of adenosine-induced sinus node dysfunction in heart failure. Failing sinoatrial node cells had slower intrinsic firing rates versus normal control cells. We were able to dem |
| 요약 | Finally, we tested the performance of an algorithm designed to allow pharmacists to manage patient serum potassium levels in patients taking antiarrhytmic medications. Due to the high risk of proarrhythmia among this population, we established a |
| 요약 | We propose that these studies provide insights into the cellular bases for the development of heart failure-induced arrhythmias, as well as optimizing management of arrhythmia in a clinical setting. |
| 일반주제명 | Pharmacology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T15000207 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024930 | DP 615 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출불가(별치) |
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