자료유형 | E-Book |
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개인저자 | Boroujerdi, Mehdi, author. |
서명/저자사항 | Pharmacokinetics and toxicokinetics /Mehdi Boroujerdi. |
형태사항 | 1 online resource |
소장본 주기 | eBooks on EBSCOhostAll EBSCO eBooks |
ISBN | 9781482221350 1482221357 |
서지주기 | Includes bibliographical references. |
내용주기 | Chapter 1. The influence of routes of administration on ADME -- chapter 2. Mechanisms of absorption and permeation of xenobiotics -- chapter 3. In Vivo distribution of xenobiotics -- chapter 4. Elimination rate, clearance, and the theoretical models -- chapter 5. Renal excretion of xenobiotics and estimation of related PK/TK parameters and constants -- chapter 6. Biotransformation of xenobiotics -- chapter 7. Kinetics of In Vitro metabolism : assimilation of intrinsic clearance in hepatic clearance -- chapter 8. Pharmaceutical, biopharmaceutical, and physiological factors influencing oral absorption : mechanistic absorption models -- chapter 9. Mathematical modeling in pharmacokinetics and toxicokinetics -- chapter 10. PK/TK analysis of instantaneous exposure to xenobiotics (single bolus injection) -- chapter 11. PK/TK analysis of continuous zero-order exposure to xenobiotics (intravenous infusion) -- chapter 12. PK/TK analysis of xenobiotics absorbed via an extravascular route of administration (oral administration) -- chapter 13. PK/TK of xenobiotics absorbed through the skin (transdermal absorption) -- chapter 14. PK/TK analysis of multiple dosing -- chapter 15. Bioavailability, bioequivalence, and biosimilar evaluations -- chapter 16. Preclinical PK/TK and clinical trials -- chapter 17. Population pharmacokinetics/toxicokinetics -- chapter 18. Quantitative extrapolation interspecies scaling/low dose extrapolation. |
요약 | The Influence of Routes of Administration on ADMEIntroductionPharmacokinetics (PK) and Pharmacodynamics (PD)Toxicokinetics (TK) and Toxicodynamics (TD)Concepts Basic to PK and TKInfluence of Routes of Exposure/Administration on PK/TK analysisBiomarkersReferencesMechanisms of Absorption and Permeation of XenobioticsIntroductionPassive DiffusionCarrier-Mediated Transcellular DiffusionTranscellular Diffusion Subject to P-Glycoprotein EffluxActive TransportEndocytosis and PinocytosisSolvent Drag, Osmosis, and Two-Pore TheoryIon-Pair AbsorptionReferencesIn Vivo Distribution of XenobioticsIntroducti. |
일반주제명 | Pharmacokinetics. Drugs -- Toxicology. MEDICAL -- Pharmacology. Drugs -- Toxicology. Pharmacokinetics. |
언어 | 영어 |
기타형태 저록 | Print version:Boroujerdi, Mehdi.Pharmacokinetics and Toxicokinetics.Hoboken : CRC Press, 짤20159781482221343 |
대출바로가기 | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=957544 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
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1 | WE00010266 | 615.7 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |