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▼a 908092012 |
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▼a 9781482221350
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▼a 1482221357
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▼a Boroujerdi, Mehdi,
▼e author. |
| 245 | 10 |
▼a Pharmacokinetics and toxicokinetics /
▼c Mehdi Boroujerdi. |
| 264 | 1 |
▼a Boca Raton, FL :
▼b CRC Press LLC,
▼c [2015] |
| 300 | |
▼a 1 online resource |
| 336 | |
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▼a Includes bibliographical references. |
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▼a Chapter 1. The influence of routes of administration on ADME -- chapter 2. Mechanisms of absorption and permeation of xenobiotics -- chapter 3. In Vivo distribution of xenobiotics -- chapter 4. Elimination rate, clearance, and the theoretical models -- chapter 5. Renal excretion of xenobiotics and estimation of related PK/TK parameters and constants -- chapter 6. Biotransformation of xenobiotics -- chapter 7. Kinetics of In Vitro metabolism : assimilation of intrinsic clearance in hepatic clearance -- chapter 8. Pharmaceutical, biopharmaceutical, and physiological factors influencing oral absorption : mechanistic absorption models -- chapter 9. Mathematical modeling in pharmacokinetics and toxicokinetics -- chapter 10. PK/TK analysis of instantaneous exposure to xenobiotics (single bolus injection) -- chapter 11. PK/TK analysis of continuous zero-order exposure to xenobiotics (intravenous infusion) -- chapter 12. PK/TK analysis of xenobiotics absorbed via an extravascular route of administration (oral administration) -- chapter 13. PK/TK of xenobiotics absorbed through the skin (transdermal absorption) -- chapter 14. PK/TK analysis of multiple dosing -- chapter 15. Bioavailability, bioequivalence, and biosimilar evaluations -- chapter 16. Preclinical PK/TK and clinical trials -- chapter 17. Population pharmacokinetics/toxicokinetics -- chapter 18. Quantitative extrapolation interspecies scaling/low dose extrapolation. |
| 520 | |
▼a The Influence of Routes of Administration on ADMEIntroductionPharmacokinetics (PK) and Pharmacodynamics (PD)Toxicokinetics (TK) and Toxicodynamics (TD)Concepts Basic to PK and TKInfluence of Routes of Exposure/Administration on PK/TK analysisBiomarkersReferencesMechanisms of Absorption and Permeation of XenobioticsIntroductionPassive DiffusionCarrier-Mediated Transcellular DiffusionTranscellular Diffusion Subject to P-Glycoprotein EffluxActive TransportEndocytosis and PinocytosisSolvent Drag, Osmosis, and Two-Pore TheoryIon-Pair AbsorptionReferencesIn Vivo Distribution of XenobioticsIntroducti. |
| 588 | 0 |
▼a Vendor-supplied metadata. |
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▼a eBooks on EBSCOhost
▼b All EBSCO eBooks |
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▼a Pharmacokinetics. |
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▼a Drugs
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▼a Pharmacokinetics.
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▼a Electronic books. |
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▼i Print version:
▼a Boroujerdi, Mehdi.
▼t Pharmacokinetics and Toxicokinetics.
▼d Hoboken : CRC Press, 짤2015
▼z 9781482221343 |
| 856 | 40 |
▼u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=957544 |
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