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020 ▼a 9780438313231
035 ▼a (MiAaPQ)AAI10618754
035 ▼a (MiAaPQ)mayo:10455
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 612
1001 ▼a Gonzalez Porras, Maria A.
24510 ▼a Mesoporous Silica Nanoparticles to Target Motoneurons.
260 ▼a [S.l.] : ▼b College of Medicine - Mayo Clinic., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 225 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Carlos B. Mantilla.
5021 ▼a Thesis (Ph.D.)--College of Medicine - Mayo Clinic, 2017.
520 ▼a Drug delivery systems to motoneurons are critical in developing effective and safe treatments for motoneuron diseases (e.g. amyotrophic lateral sclerosis), as well as in understanding causes of muscle denervation (e.g. spinal cord injury, or age
520 ▼a The use of nanoparticles to target the delivery of drugs can potentially ameliorate a number of problems exhibited by conventional 'free' drugs, including poor solubility, limited stability, rapid clearing, and, in particular, lack of selectivit
590 ▼a School code: 1542.
650 4 ▼a Physiology.
650 4 ▼a Nanoscience.
690 ▼a 0719
690 ▼a 0565
71020 ▼a College of Medicine - Mayo Clinic. ▼b Biomedical Engineering.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 1542
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996639 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자