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008181129s2017 |||||||||||||||||c||eng d
020 ▼a 9780438029071
035 ▼a (MiAaPQ)AAI10616011
035 ▼a (MiAaPQ)utah:13954
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 615
1001 ▼a Cheng, Yan.
24510 ▼a Adherence Pattern, Health Care Utilization, and Virologic Outcomes among Treatment-naive Veteran Patients with Human Immunodeficiency Virus Type 1 Infection.
260 ▼a [S.l.] : ▼b The University of Utah., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 158 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
500 ▼a Adviser: Joanne LaFleur.
5021 ▼a Thesis (Ph.D.)--The University of Utah, 2017.
520 ▼a Many studies have estimated the treatment effect of different antiretroviral therapies (ARTs) on human immunodeficiency virus (HIV) patients' virologic/immunologic outcomes. However, evidence is lacking on how adherence to ARTs influences treatm
520 ▼a The goal of this study is to explore HIV treatment-naive veterans' health care utilization and to investigate the effect of early adherence on initial viral suppression by different regimens.
520 ▼a A cohort study was conducted on HIV veterans initiating ARTs in 1999--2015. The follow-up time was one year since the first fill of base agent (index date). Patients' health care utilization during the follow-up as well as the correlations betwe
520 ▼a Data showed that all patients had at least one follow-up test or visit in the one year. The mean of initial adherence to the base agent was 0.84--0.90, depending on the regimens, with unboosted protease inhibitors (PIs) lowest and integrase inhi
520 ▼a Initial adherence differently influenced the viral suppression rate across different regimens. Regardless of regimen categories, no evidence shows 95% adherence threshold is necessary.
590 ▼a School code: 0240.
650 4 ▼a Pharmaceutical sciences.
690 ▼a 0572
71020 ▼a The University of Utah. ▼b Pharmacotherapy.
7730 ▼t Dissertation Abstracts International ▼g 79-10B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0240
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996632 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자