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020 ▼a 9780438353114
035 ▼a (MiAaPQ)AAI10615208
035 ▼a (MiAaPQ)umn:18426
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Tasca, Amy Ward.
24514 ▼a The Role of Myosin X in BMPs Promotion of SMAD 1/5 in Osteoclast Formation and Function.
260 ▼a [S.l.] : ▼b University of Minnesota., ▼c 2017
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2017
300 ▼a 105 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Kim Mansky.
5021 ▼a Thesis (Ph.D.)--University of Minnesota, 2017.
520 ▼a Novel therapeutic strategies that target osteoclasts are needed for many orthopedic, craniofacial and cancer applications. Incomplete understanding of the factors that regulate osteoclasts limits this development. Currently, bone morphogenetic p
520 ▼a The data presented in this thesis demonstrates that loss of SMAD1/5 expression by osteoclasts in in vitro cultures of osteoclasts inhibits osteoclast differentiation and activity. However, the loss of SMAD1/5 expression in osteoclasts and macrop
590 ▼a School code: 0130.
650 4 ▼a Biology.
690 ▼a 0306
71020 ▼a University of Minnesota. ▼b Oral Biology.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0130
791 ▼a Ph.D.
792 ▼a 2017
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996630 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자