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020 ▼a 9780438159426
035 ▼a (MiAaPQ)AAI10189847
035 ▼a (MiAaPQ)wisc:13603
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 574
1001 ▼a Ren, Jun.
24514 ▼a The Paracrine Function of Smooth Muscle Cells in Vascular Injury and Repair.
260 ▼a [S.l.] : ▼b The University of Wisconsin - Madison., ▼c 2016
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2016
300 ▼a 269 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
500 ▼a Adviser: Bo Liu.
5021 ▼a Thesis (Ph.D.)--The University of Wisconsin - Madison, 2016.
520 ▼a Vascular smooth muscle cells (SMCs) play a critical role in vascular pathogenesis including intimal hyperplasia (IH), atherosclerosis, and aneurysms. It is generally believed that SMCs respond to vascular injury with apoptosis, loss of contracti
520 ▼a In my thesis work, I utilized an apoptotic mediator protein kinase C-delta (PKCdelta) to stress SMCs. The thesis is organized into five chapters. In Chapter 1, I provide a brief review of the accumulating knowledge regarding vascular injury resp
520 ▼a In sum, data generated through my dissertation provide experimental proof that stressed SMCs communicate with other cell types through PKCdelta-mediated paracrine signals after vascular injury. These paracrine signals released by stressed SMCs h
590 ▼a School code: 0262.
650 4 ▼a Biology.
650 4 ▼a Cellular biology.
650 4 ▼a Molecular biology.
690 ▼a 0306
690 ▼a 0379
690 ▼a 0307
71020 ▼a The University of Wisconsin - Madison. ▼b Endocrinol-Reprod Physiol - AG.
7730 ▼t Dissertation Abstracts International ▼g 79-11B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0262
791 ▼a Ph.D.
792 ▼a 2016
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996501 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자