| LDR | | 02396nmm uu200457 4500 |
| 001 | | 000000334470 |
| 005 | | 20240805180352 |
| 008 | | 181129s2016 |||||||||||||||||c||eng d |
| 020 | |
▼a 9780438030572 |
| 035 | |
▼a (MiAaPQ)AAI10188280 |
| 035 | |
▼a (MiAaPQ)umn:16851 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 082 | 0 |
▼a 575 |
| 100 | 1 |
▼a Schultz, Nichol Elizabeth. |
| 245 | 10 |
▼a Characterization of Equine Metabolic Syndrome and Mapping of Candidate Genetic Loci. |
| 260 | |
▼a [S.l.] :
▼b University of Minnesota.,
▼c 2016 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2016 |
| 300 | |
▼a 375 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B. |
| 500 | |
▼a Advisers: James R. Mickelson |
| 502 | 1 |
▼a Thesis (Ph.D.)--University of Minnesota, 2016. |
| 520 | |
▼a Equine metabolic syndrome (EMS) is a clustering of clinical signs associated with increased risk of laminitis, a potentially life-threatening condition of the foot. Similar to human metabolic syndrome (MetS), generalized and/or regional adiposit |
| 520 | |
▼a Chapter 2 details the largest-ever epidemiological investigation of EMS in which 11 metabolic traits were measured in >600 horses and ponies from 166 farms. The use of multivariate, multilevel regression modeling allowed, for the first time, qua |
| 520 | |
▼a Differences in the incretin response may also contribute to individual trait variation. The incretin response, defined as the difference in insulinemic responses between an oral and intravenous glucose challenge, is controlled by intestinal secr |
| 520 | |
▼a In Chapter 4, an improved linear mixed model for mapping polygenic traits in a population with familial relationships similar to that in many equine GWAS was developed and validated. The model incorporates a Bayesian variable selection method to |
| 590 | |
▼a School code: 0130. |
| 650 | 4 |
▼a Genetics. |
| 650 | 4 |
▼a Animal diseases. |
| 650 | 4 |
▼a Statistics. |
| 690 | |
▼a 0369 |
| 690 | |
▼a 0476 |
| 690 | |
▼a 0463 |
| 710 | 20 |
▼a University of Minnesota.
▼b Comparative and Molecular Biosciences. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 79-10B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0130 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2016 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T14996465
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자 |