MARC보기
LDR01969nmm uu200385 4500
001000000334435
00520240805180310
008181129s2018 |||||||||||||||||c||eng d
020 ▼a 9780438364790
035 ▼a (MiAaPQ)AAI10984420
040 ▼a MiAaPQ ▼c MiAaPQ ▼d 248032
0820 ▼a 616
1001 ▼a Shaaban, C. Elizabeth.
24510 ▼a Promoters of Cerebral Small Vessel Integrity for Cognitive Disorder Prevention.
260 ▼a [S.l.] : ▼b University of Pittsburgh., ▼c 2018
260 1 ▼a Ann Arbor : ▼b ProQuest Dissertations & Theses, ▼c 2018
300 ▼a 201 p.
500 ▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
500 ▼a Adviser: Caterina Rosano.
5021 ▼a Thesis (Ph.D.)--University of Pittsburgh, 2018.
520 ▼a The unique metabolic demands of the brain point to the critical nature of cerebral small vessel integrity for overall brain and cognitive health. Given the lack of any diseasemodifying treatments, new avenues for Alzheimer's disease (AD) prevent
520 ▼a Existing methods of evaluating cerebral small vessel integrity focus on neuroimaging markers distal to small vessel disease and fail to evaluate the vessels themselves. To address this limitation, I developed a method using 7T susceptibilityweig
520 ▼a In an era when multimorbidity is common among older adults, interactions involving vascular and cardiometabolic risk factors (VCMRF) are critical to evaluate in order to effectively target preventions and treatments---the promise of precision me
590 ▼a School code: 0178.
650 4 ▼a Neurosciences.
690 ▼a 0317
71020 ▼a University of Pittsburgh. ▼b Public Health.
7730 ▼t Dissertation Abstracts International ▼g 80-01B(E).
773 ▼t Dissertation Abstract International
790 ▼a 0178
791 ▼a Ph.D.
792 ▼a 2018
793 ▼a English
85640 ▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001394 ▼n KERIS
980 ▼a 201812 ▼f 2019
990 ▼a 관리자