LDR | | 01969nmm uu200385 4500 |
001 | | 000000334435 |
005 | | 20240805180310 |
008 | | 181129s2018 |||||||||||||||||c||eng d |
020 | |
▼a 9780438364790 |
035 | |
▼a (MiAaPQ)AAI10984420 |
040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
082 | 0 |
▼a 616 |
100 | 1 |
▼a Shaaban, C. Elizabeth. |
245 | 10 |
▼a Promoters of Cerebral Small Vessel Integrity for Cognitive Disorder Prevention. |
260 | |
▼a [S.l.] :
▼b University of Pittsburgh.,
▼c 2018 |
260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2018 |
300 | |
▼a 201 p. |
500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
500 | |
▼a Adviser: Caterina Rosano. |
502 | 1 |
▼a Thesis (Ph.D.)--University of Pittsburgh, 2018. |
520 | |
▼a The unique metabolic demands of the brain point to the critical nature of cerebral small vessel integrity for overall brain and cognitive health. Given the lack of any diseasemodifying treatments, new avenues for Alzheimer's disease (AD) prevent |
520 | |
▼a Existing methods of evaluating cerebral small vessel integrity focus on neuroimaging markers distal to small vessel disease and fail to evaluate the vessels themselves. To address this limitation, I developed a method using 7T susceptibilityweig |
520 | |
▼a In an era when multimorbidity is common among older adults, interactions involving vascular and cardiometabolic risk factors (VCMRF) are critical to evaluate in order to effectively target preventions and treatments---the promise of precision me |
590 | |
▼a School code: 0178. |
650 | 4 |
▼a Neurosciences. |
690 | |
▼a 0317 |
710 | 20 |
▼a University of Pittsburgh.
▼b Public Health. |
773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
773 | |
▼t Dissertation Abstract International |
790 | |
▼a 0178 |
791 | |
▼a Ph.D. |
792 | |
▼a 2018 |
793 | |
▼a English |
856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001394
▼n KERIS |
980 | |
▼a 201812
▼f 2019 |
990 | |
▼a 관리자 |