| LDR | | 00000nmm u2200205 4500 |
| 001 | | 000000334397 |
| 005 | | 20250204101110 |
| 008 | | 181129s2016 ||| | | | eng d |
| 020 | |
▼a 9780438310070 |
| 035 | |
▼a (MiAaPQ)AAI10970766 |
| 035 | |
▼a (MiAaPQ)OhioLINK:osu1461086954 |
| 040 | |
▼a MiAaPQ
▼c MiAaPQ
▼d 248032 |
| 049 | 1 |
▼f DP |
| 082 | 0 |
▼a 574 |
| 100 | 1 |
▼a Small, Lawrence E. |
| 245 | 10 |
▼a PAR Proteins Regulate CDC-42-Dependent Myosin Dynamics During C. elegans Zygote Polarization. |
| 260 | |
▼a [S.l.] :
▼b The Ohio State University.,
▼c 2016 |
| 260 | 1 |
▼a Ann Arbor :
▼b ProQuest Dissertations & Theses,
▼c 2016 |
| 300 | |
▼a 111 p. |
| 500 | |
▼a Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B. |
| 500 | |
▼a Adviser: Adriana Dawes. |
| 502 | 1 |
▼a Thesis (Ph.D.)--The Ohio State University, 2016. |
| 520 | |
▼a Establishment of anterior-posterior polarity in the C. elegans zygote requires two different processes: mechanical activity of the actin-myosin cortex and biochemical activity of partitioning defective (PAR) proteins. Here, we have analyzed how |
| 520 | |
▼a We then have extended the themes of this work to hypothesize how crosstalk between PAR proteins and Rho GTPases may be at work in other biological contexts, and we propose how improved mathematical modeling will increase our understanding of thi |
| 520 | |
▼a In summary, the work presented in this dissertation increases our understanding of the several ways that PAR signaling can influence Rho GTPase in the context of myosin dynamics. We have applied this new understanding and other work in the field |
| 590 | |
▼a School code: 0168. |
| 650 | 4 |
▼a Cellular biology. |
| 650 | 4 |
▼a Molecular biology. |
| 650 | 4 |
▼a Genetics. |
| 650 | 4 |
▼a Biology. |
| 690 | |
▼a 0379 |
| 690 | |
▼a 0307 |
| 690 | |
▼a 0369 |
| 690 | |
▼a 0306 |
| 710 | 20 |
▼a The Ohio State University.
▼b Molecular Genetics. |
| 773 | 0 |
▼t Dissertation Abstracts International
▼g 80-01B(E). |
| 773 | |
▼t Dissertation Abstract International |
| 790 | |
▼a 0168 |
| 791 | |
▼a Ph.D. |
| 792 | |
▼a 2016 |
| 793 | |
▼a English |
| 856 | 40 |
▼u http://www.riss.kr/pdu/ddodLink.do?id=T15001356
▼n KERIS |
| 980 | |
▼a 201812
▼f 2019 |
| 990 | |
▼a 관리자
▼b 정현우 |